Next Generation Organ on Chip Technology
Tissue Dynamics Ltd. is a groundbreaking biotechnology company that develops drug toxicity and efficacy screening tools for the pharmaceutical and cosmetic industries.
Tissue Dynamics proprietary high throughput kinetic screening platform utilizes sensor-integrated organ on chip technology to monitor changes in metabolic function in real time. Our micro-physiological platform utilizes real time data acquisition to minimize false positive and false negative-type errors.
Our technology detects stress at concentrations far below the threshold of cellular damage, elucidating mechanism of action without a priori information, highlighting idiosyncratic toxicity risk.
Cells and micro-sensors loaded together into microwells
Complex 3D bionic
micro-tissues form overnight
Metabolic function is measured every few minutes up to 28 days followed by risk assessment
"Animal testing alternative breakthrough... a liver-on-chip device mimicking human physiology " Horizon 2020, Aug. 15, 2015
"Acetaminophen toxic at lower levels than thought"
UPI, Aug. 17, 2015
"Liver-simulating device surpasses animal-based alternatives"
European Commission, Oct. 30, 2015
"Novel technology allows assessment of drug induced mitochondrial damage"
GEN News Highlights, Apr. 5, 2016
"Microchip offers insight into dynamics of cellular function"
Jerusalem Post, May. 28, 2016
"Scientists invent bionic micro-livers to replace animal testing"
Haaretz, Nov. 2, 2016
This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 827858